The software used in our practice and in accord with client needs is:
NONMEM® for population PK PD modeling and some simulations
WinNonlin® for single subject PK PD modeling
S-Plus (S+) ® for data management, graphing, linear and nonlinear modeling, trial simulations, presentation creation
PK-Sim® for pre-clinical alometry and physiological simulations
SPSS for statistics